Synthesis of single and tandem dna damages and mutagenesis studies of gamma-radiation-induced cross-linked guanine-thymine tandem lesion

The common environmental pollutant 1-nitropyrene and ionizing radiation are two examples of DNA damaging agents. Both these agents are mutagenic, tumorigenic, and carcinogenic. The reductive activation of the carcinogen 1-nitropyrene forms a C8 2'-deoxyguanosine adduct, N-(deoxyguanosin-8-yl)-1...

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Bibliographic Details

Main Author:	Colis, Laureen C. (Author)
Resource Type:	Electronic Resource
Language:	English
Published:	Ann Arbor Michigan ProQuest Information and Learning Company [2007]
Subjects:	Mutagenesis.
Online Access:	Full text access requires UP Webmail login