The role of the alternative pathway of the complement system in the development of dense deposit disease

"Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of...

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Dettagli Bibliografici
Autore principale:	Abeleda, Maria Asuncion Abrera (Autore)
Ente Autore:	University of Iowa
Altri autori:	Smith, Richard H. (advisor.)
Natura:	Electronic Resource
Lingua:	English
Pubblicazione:	Ann Arbor, MI ProQuest Dissertations & Theses Global [2010]
Soggetti:	Electronic books. Kidneys > Diseases > Genetic aspects. Alternative pathway > Animal models > Association studies > Complement activity > Complement system > Dense deposit disease.
Accesso online:	Full text access requires UP Webmail login