The role of the alternative pathway of the complement system in the development of dense deposit disease

The role of the alternative pathway of the complement system in the development of dense deposit disease

"Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of...

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מידע ביבליוגרפי
מחבר ראשי: Abeleda, Maria Asuncion Abrera (Author)
מחבר תאגידי: University of Iowa
מחברים אחרים: Smith, Richard H. (advisor.)
פורמט: Electronic Resource
שפה:English
יצא לאור: Ann Arbor, MI ProQuest Dissertations & Theses Global [2010]
נושאים:
Electronic books.
Kidneys > Diseases > Genetic aspects.
Alternative pathway > Animal models > Association studies > Complement activity > Complement system > Dense deposit disease.
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