The role of the alternative pathway of the complement system in the development of dense deposit disease

The role of the alternative pathway of the complement system in the development of dense deposit disease

"Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of...

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Bibliographic Details
Main Author: Abeleda, Maria Asuncion Abrera (Author)
Corporate Author: University of Iowa
Other Authors: Smith, Richard H. (advisor.)
Format: Electronic Resource
Language:English
Published: Ann Arbor, MI ProQuest Dissertations & Theses Global [2010]
Subjects:
Electronic books.
Kidneys > Diseases > Genetic aspects.
Alternative pathway > Animal models > Association studies > Complement activity > Complement system > Dense deposit disease.
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