The role of the alternative pathway of the complement system in the development of dense deposit disease

"Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of...

Descrición completa

Detalles Bibliográficos
Autor Principal:	Abeleda, Maria Asuncion Abrera (Author)
Autor Corporativo:	University of Iowa
Outros autores:	Smith, Richard H. (advisor.)
Formato:	Electronic Resource
Idioma:	English
Publicado:	Ann Arbor, MI ProQuest Dissertations & Theses Global [2010]
Subjects:	Electronic books. Kidneys > Diseases > Genetic aspects. Alternative pathway > Animal models > Association studies > Complement activity > Complement system > Dense deposit disease.
Acceso en liña:	Full text access requires UP Webmail login