The role of the alternative pathway of the complement system in the development of dense deposit disease

The role of the alternative pathway of the complement system in the development of dense deposit disease

"Dense Deposit Disease (DDD) causes chronic renal dysfunction which progresses to end-stage renal disease in about half of patients within 10 years of diagnosis. Deficiency of and mutations in complement Factor H (CFH) are associated with the development of DDD, suggesting that dysregulation of...

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書目詳細資料
主要作者: Abeleda, Maria Asuncion Abrera (Author)
企業作者: University of Iowa
其他作者: Smith, Richard H. (advisor.)
格式: Electronic Resource
語言:English
出版: Ann Arbor, MI ProQuest Dissertations & Theses Global [2010]
主題:
Electronic books.
Kidneys > Diseases > Genetic aspects.
Alternative pathway > Animal models > Association studies > Complement activity > Complement system > Dense deposit disease.
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