A computationally efficient algorithm for determining regional cerebral blood flow in heterogeneous tissues by positron emission tomography.

Inclusion of brain tissues with different rates of blood flow and metabolism within a voxel or region of interest is an unavoidable problem with positron emission tomography due to its limited spatial resolution. Because regional cerebral blood flow (rCBF) is higher in gray matter than in white matt...

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Bibliographic Details
Published in:	IEEE Transactions on medical imaging 20, 7 (2001).
Main Author:	Schmidt, K.
Format:	Article
Language:	English
Subjects:	PET. Computationally efficient algorithm. Gray matter. Homogeneous tissues mixture. Kinetic model. Limited spatial resolution. Linear least squares algorithm. Medical diagnostic imaging. Metabolism. Model parameters estimation. Nuclear medicine. Region of interest. Regional cerebral blood flow determination. Voxel. White matter.