Application of Simulated Annealing to the Biclustering of Gene Expression Data.

In a gene expression data matrix, a bicluster is a submatrix of genes and conditions that exhibits a high correlation of expression activity across both rows and columns. The problem of locating the most significant bicluster has been shown to be NP-complete. Heuristic approaches such as Cheng and C...

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Bibliographic Details

Published in:	IEEE Transactions on information technology in biomedicine 10, 3 (2006).
Main Author:	Bryan, K.
Format:	Article
Language:	English
Subjects:	Biclustering. Data mining. Evolutionary algorithm. Gene expression data matrix. Greedy node deletion algorithm. Heuristic approach. Simulated annealing. Stochastic search technique.