Addressing cell-sourcing limitations with gene therapy.

Genetic engineering with Run×2/Cbfa 1 for an alternative to biological grafts. Forced Runx2 expression via retroviral gene delivery promotes osteoblastic differentiation and mineralization in bone marrow stromal cells and stimulates conversion of myoblasts and dermal fibroblasts into a mineralizing...

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Xuất bản năm:	IEEE Engineering in medicine and biology magazine 22, 5 (2003).
Tác giả chính:	Garcia, A.J
Định dạng:	Bài viết
Ngôn ngữ:	English
Những chủ đề:	Bone marrow stromal cells. Bone tissue engineering. Cell-sourcing limitations. Dermal fibroblasts. Genetic engineering strategy. Mineralization. Mineralizing osteoblastic phenotype. Osteoblastic differentiation. Retroviral gene delivery.