Addressing cell-sourcing limitations with gene therapy.

Genetic engineering with Run×2/Cbfa 1 for an alternative to biological grafts. Forced Runx2 expression via retroviral gene delivery promotes osteoblastic differentiation and mineralization in bone marrow stromal cells and stimulates conversion of myoblasts and dermal fibroblasts into a mineralizing...

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Bibliografski detalji

Izdano u:	IEEE Engineering in medicine and biology magazine 22, 5 (2003).
Glavni autor:	Garcia, A.J
Format:	Članak
Jezik:	English
Teme:	Bone marrow stromal cells. Bone tissue engineering. Cell-sourcing limitations. Dermal fibroblasts. Genetic engineering strategy. Mineralization. Mineralizing osteoblastic phenotype. Osteoblastic differentiation. Retroviral gene delivery.