Dynamic magnetic resonance imaging of tumor perfusion.

This work presents approaches and biomedical challenges of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). DCE-MRI using small molecular weight gadolinium chelates enables noninvasive imaging characterization of tissue vascularity. Depending on the technique used, data reflecting tis...

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Bibliographic Details
Published in:	IEEE Engineering in medicine and biology magazine 23, 5 (2004).
Main Author:	Collins, D.J
Format:	Article
Language:	English
Subjects:	Antivascular anticancer drugs. Arterial input function. Blood flow. Blood volume. Complex compartmental modeling techniques. Dynamic magnetic resonance imaging. Extracellular leakage space. Kinetic enhancement curves. Kinetic modeling processes. Lesion characterization. Malignant disease screening. Mean transit time. Microvessel permeability surface area product. Noninvasive imaging characterization. Pharmacodynamic assessments. Prognostication. Robust analysis software. Small molecular weight gadolinium chelates. Tissue perfusion. Tissue vascularity. Treatment efficacy. Tumor perfusion. Validated statistical tools.