Robust term-wise parameter estimation in biochemical Generalized Mass Action (GMA) models by hybrid regularized least squares-particle swarm optimization

High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopy generate time dense profile of metabolites or proteins that contain structural and kinetic information about the underlying system that produced them. Experimentalists are...

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Bibliographic Details
Main Author: Naval, Prospero C.
Format: Thesis
Language:English
Published: 2007.
Subjects: