One-factor-at-a-time-guided development of simvastatin-loaded alginate-chitosan microspheres

Pursuant to the concept of quality by design, recent trends in polymer-based drug delivery system research utilize design of experiments (DOE) to systematically identify factor levels that yield optimal responses. One-factor-at-a-time (OFAT) guided experiments remain useful in providing a basis for...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Carlos, Sophia Isabelle R. (مؤلف)
مؤلفون آخرون:	Goyena, Aianna Jennine R. (author .), Honasan, Joana Pauline L. (author .), Bryan Paul I. Bulatao (adviser.), Julius Andrew P. Nuñez (co-adviser.)
التنسيق:	أطروحة
اللغة:	English
الموضوعات:	Drug delivery systems > Microspheres > Alginate-chitosan > Simvastatin. Controlled release preparations > Experimental design > One-factor-at-a-time method. Simvastatin > Pharmaceutical formulation > Biopolymer-based microspheres. simvastatin. OFAT. microspheres. particle size. encapsulation efficiency. loading capacity.