One-factor-at-a-time-guided development of simvastatin-loaded alginate-chitosan microspheres

Pursuant to the concept of quality by design, recent trends in polymer-based drug delivery system research utilize design of experiments (DOE) to systematically identify factor levels that yield optimal responses. One-factor-at-a-time (OFAT) guided experiments remain useful in providing a basis for...

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Bibliographic Details
Main Author:	Carlos, Sophia Isabelle R. (Author)
Other Authors:	Goyena, Aianna Jennine R. (author .), Honasan, Joana Pauline L. (author .), Bryan Paul I. Bulatao (adviser.), Julius Andrew P. Nuñez (co-adviser.)
Format:	Thesis
Language:	English
Subjects:	Drug delivery systems > Microspheres > Alginate-chitosan > Simvastatin. Controlled release preparations > Experimental design > One-factor-at-a-time method. Simvastatin > Pharmaceutical formulation > Biopolymer-based microspheres. simvastatin. OFAT. microspheres. particle size. encapsulation efficiency. loading capacity.