Development, characterization, and optimization of Losartan-Hydrochorothiazide loaded poly (D,L-Lactide-co-glycolide) (PLGA) nano particles.

Hypertension is a prevalent chronic discase that requires patient compliance for successful therapy. However, patients become non-adherent and discontinue medication due to complexity of medication, required dosing frequency, and undesirable drug reactions. Losartan- hydrochlorothiazide (HCTZ), a wi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Bacud, Karen Joy B. (VerfasserIn), Bacud, Karen Joy B. Geron (VerfasserIn), Elyza Marie Santos, Maraiah Shannen T. (VerfasserIn)
Weitere Verfasser:	Casauay, Jean Flor C. (adviser.)
Format:	Abschlussarbeit
Sprache:	English
Schlagworte:	Losartan > Nanoparticles > Drug delivery systems > Optimization. Hydrochlorothiazide > PLGA nanoparticles > Characterization. Losartan-HCTZ. PLGA. PVA. nanoparticles. double emulsion solvent evaporation.