Development, characterization, and optimization of Losartan-Hydrochorothiazide loaded poly (D,L-Lactide-co-glycolide) (PLGA) nano particles.

Development, characterization, and optimization of Losartan-Hydrochorothiazide loaded poly (D,L-Lactide-co-glycolide) (PLGA) nano particles.

Hypertension is a prevalent chronic discase that requires patient compliance for successful therapy. However, patients become non-adherent and discontinue medication due to complexity of medication, required dosing frequency, and undesirable drug reactions. Losartan- hydrochlorothiazide (HCTZ), a wi...

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Bibliographic Details
Main Authors: Bacud, Karen Joy B. (Author), Bacud, Karen Joy B. Geron (Author), Elyza Marie Santos, Maraiah Shannen T. (Author)
Other Authors: Casauay, Jean Flor C. (adviser.)
Format: Thesis
Language:English
Subjects:
Losartan > Nanoparticles > Drug delivery systems > Optimization.
Hydrochlorothiazide > PLGA nanoparticles > Characterization.
Losartan-HCTZ.
PLGA.
PVA.
nanoparticles.
double emulsion solvent evaporation.