Formulation development and evaluation of layer-by-layer alginate/chitosan-coated microspheres loaded with simvastatin

Simvastatin (SMV) is a highly lipophilic drug that demonstrates poor bioavailability. This issue could be resolved through microencapsulation with the use of alginate (ALG) and chitosan (CS). We aimed to prepare and evaluate SMV-loaded microspheres coated with alternating layers of ALG and CS throug...

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Bibliografiske detaljer
Hovedforfatter:	Bernardo, Robert Joseph V.
Andre forfattere:	Enriquez, Carlos Martin L. (author .), Ramos, Portia Rochelle C. (author .), Bulatao, Bryan Paul I. (adviser.)
Format:	Thesis
Sprog:	English
Fag:	Drug delivery systems > Microspheres > Alginates > Chitosan. Therapeutic uses > Drug carriers > Coating processes. Controlled release preparations > Pharmaceutical technology > Philippines. Simvastatin .