Evaluation of the effects of ethyl cellulose and polyvinyl alcohol mass ratio on the characteristic of simvastatin-loaded polymer-based matrix patch for transdermal delivery

Simvastatin (SMV) is a widely prescribed statin that lowers cholesterol levels and is commonly available in its oral dosage form. However, SMV has a low bioavailability due to first-pass metabolism, making it a suitable candidate for transdermal drug delivery. The study aimed to screen the factors t...

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