In silico studies on N- (Pyridin-2-yl) Thiobenzamides as NNRTIs against wild and mutant HIV-1 strains

In the present study, keeping the Lipinskiâ??s Rule of Five in focus, a series of new 4-(4-benzenesulfonylamino)-N-(5-substituted-pyridin-2-yl)-thiobenzamides bearing different substituents at the C-4 position of benzenesulfonylamino ring have been designed as NNRTIs of wild-type (WT) and mutant HIV...

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Auteurs principaux:	Singh, Anuradha (Auteur), Singh, Vishal Kumar (Auteur), Verma,Rajesh (Auteur), Singh, Ramendra K. (Auteur)
Format:	Analytics
Langue:	anglais
Publié:	2018.
Sujets:	Chemistry. Lipinski?s rule of five. Hiv-1 reverse transcription. Structure-activity relationships (sars).
Accès en ligne:	https://forms.gle/KZjBv7aRtY6jiL5E9