Development of adjuvant for oral cholera vaccine prepared from combined vibrio cholerae antigens
Liposomes were prepared from bovins brain sphingomyelin and cholesterol. They were reinforced by incorporation of osmium tetroxide to prevent their immediate degradation inside the host. Combined V. cholerae antigens (LPS, CHA and P) were orally administered to experimental rats either as free or o...
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| Format: | Thèse |
| Langue: | English |
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1989.
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