Development of predictive PBPK model for extended-release metformin tablets through Simcyp software

Physiologically Based Pharmacokinetic (PBPK) models integrate the physiological, physicochemical and biochemical processes that determine the pharmacokinetic behavior of a compound such as metformin. PBPK Modelling using the Simcyp software can be applied as a method for requesting biowaivers. Model...

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Detalhes bibliográficos

Principais autores:	Legaspi, Donato Jr. D. (Autor), Ngo, Frances Lois U. (Autor), Olayan, Imma Coney P. (Autor)
Outros Autores:	Bulatao, Bryan Paul I. (thesis adviser.)
Formato:	Tese
Idioma:	English
Publicado em:	​​​​​​​​​​Manila: Department of Industrial Pharmacy, College of Pharmacy, University of the Philippines Manila 2017. ​​
Assuntos:	Metformin.