Development of predictive PBPK model for extended-release metformin tablets through Simcyp software
Physiologically Based Pharmacokinetic (PBPK) models integrate the physiological, physicochemical and biochemical processes that determine the pharmacokinetic behavior of a compound such as metformin. PBPK Modelling using the Simcyp software can be applied as a method for requesting biowaivers. Model...
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| Format: | Thesis |
| Idioma: | English |
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Manila: Department of Industrial Pharmacy, College of Pharmacy, University of the Philippines Manila
2017.
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