Development of predictive PBPK model for extended-release metformin tablets through Simcyp software

Physiologically Based Pharmacokinetic (PBPK) models integrate the physiological, physicochemical and biochemical processes that determine the pharmacokinetic behavior of a compound such as metformin. PBPK Modelling using the Simcyp software can be applied as a method for requesting biowaivers. Model...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Legaspi, Donato Jr. D. (Συγγραφέας), Ngo, Frances Lois U. (Συγγραφέας), Olayan, Imma Coney P. (Συγγραφέας)
Άλλοι συγγραφείς:	Bulatao, Bryan Paul I. (thesis adviser.)
Μορφή:	Thesis
Γλώσσα:	English
Έκδοση:	​​​​​​​​​​Manila: Department of Industrial Pharmacy, College of Pharmacy, University of the Philippines Manila 2017. ​​
Θέματα:	Metformin.