Development of predictive PBPK model for extended-release metformin tablets through Simcyp software

Physiologically Based Pharmacokinetic (PBPK) models integrate the physiological, physicochemical and biochemical processes that determine the pharmacokinetic behavior of a compound such as metformin. PBPK Modelling using the Simcyp software can be applied as a method for requesting biowaivers. Model...

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Bibliographic Details

Main Authors:	Legaspi, Donato Jr. D. (Author), Ngo, Frances Lois U. (Author), Olayan, Imma Coney P. (Author)
Other Authors:	Bulatao, Bryan Paul I. (thesis adviser.)
Format:	Thesis
Language:	English
Published:	​​​​​​​​​​Manila: Department of Industrial Pharmacy, College of Pharmacy, University of the Philippines Manila 2017. ​​
Subjects:	Metformin.