Development of predictive PBPK model for extended-release metformin tablets through Simcyp software

Physiologically Based Pharmacokinetic (PBPK) models integrate the physiological, physicochemical and biochemical processes that determine the pharmacokinetic behavior of a compound such as metformin. PBPK Modelling using the Simcyp software can be applied as a method for requesting biowaivers. Model...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Legaspi, Donato Jr. D. (VerfasserIn), Ngo, Frances Lois U. (VerfasserIn), Olayan, Imma Coney P. (VerfasserIn)
Weitere Verfasser: Bulatao, Bryan Paul I. (thesis adviser.)
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: ​​​​​​​​​​Manila: Department of Industrial Pharmacy, College of Pharmacy, University of the Philippines Manila 2017. ​​
Schlagworte: