Protein engineering for therapeutics part A - Wittrup, K. Dane.; Verdine, Gregory L. (San Diego, CA Elsevier/Academic Press, 2012)
Simplified synthetic antibody libraries / Saravanan Rajan, Sachdev S. Sidhu -- Generation of dual-variable-domain immunoglobulin molecules for dual-specific targeting / Jijie Gu, Tariq Ghayur -- Discovery of internalizing antibodies to tumor antigens from phage libraries / Yu Zhou, James D. Marks -- Optimizing properties of antireceptor antibodies using kinetic computational models and experiments / Brian D. Harms [and others] -- Cell-specific siRNA delivery by peptides and antibodies / Sang-Kyung Lee [and others] -- Conjugation of anticancer drugs through endogenous monoclonal antibody cysteine residues / Robert P. Lyon [and others] -- Building and characterizing antibody-targeted lipidic nanotherapeutics / Dmitri B. Kirpotin [and others] -- Cell-targeting fusion constructs containing recombinant gelonin / Mi-Ae Lyu [and others] -- Fusions of elastin-like polypeptides to pharmaceutical proteins / Wafa Hassouneh, Sarah R. MacEwan, Ashutosh Chilkoti -- Oral enzyme therapy for celiac sprue / Michael T. Bethune, Chaitan Khosla -- Rational design and evaluation of mammalian ribonuclease cytotoxins / Jo E. Lomax, Chelcie H. Eller, Ronald T. Raines -- Engineering reduced-immunogenicity enzymes for amino acid depletion therapy in cancer / Jason R. Cantor [and others]
Includes bibliographical references and indexes.
Keywords: Protein engineering; Proteins -- Research; Pharmacokinetics; Electronic books