The unfolded protein response and cellular stress part B - Conn, P. Michael (San Diego, CA Elsevier/Academic Press, 2011)
Methods for investigating the UPR in filamentous fungi -- Assays for detecting the unfolded protein response -- Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells -- Measuring ER stress and the unfolded protein response using mammalian tissue culture system -- Real-time monitoring of ER stress in living cells and animals using ESTRAP assay -- HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells -- Dexamethasone induction of a heat stress response -- Detecting and quantitating physiological endoplasmic reticulum stress -- PI 3-kinase regulatory subunits as regulators of the unfolded protein response -- The emerging role of histone deacetylases (HDACs) in UPR regulation -- Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network -- Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins -- Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells -- The endoplasmic reticulum-associated degradation and disulfide reductase ERdj5 -- Structural insight into the protective role of P58(IPK) during unfolded protein response -- Principles of IRE1 modulation using chemical tools -- Methods to study stromal-cell derived factor 2 in the context of ER stress and the unfolded protein response in Arabidopsis thaliana -- Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase -- Methods for analyzing eIF2 kinases and translational control in the unfolded protein response
Includes bibliographical references and indexes.
Keywords: Cell physiology; Cellular control mechanisms; Proteins; Stress (Physiology); Proteins -- Denaturation; Analytical chemistry -- Technique; Electronic books