00000cmm a2200000 i 4500 UP-99796217613577775 Buklod 20230508141144.0 m |o d | ta 230508t20172017xx u eng d 9780128009345 (eBook) (iLib)UPD-00522071790 MiAaPQ DENGII rda eng DMLUC QD 181 N1 C44 2017eb The chemistry and biology of nitroxyl (HNO) Fabio Doctorovich, Patrick J. Farmer, Marcelo A. Marti, editors. Amsterdam Elsevier [2017] 1 online resource. text rdacontent computer rdamedia online resource rdacarrier IP based subscription, on campus and remote access. Access via Electronic Resources of the UPD Engineering Library and University Library websites. The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues.--Provided by publisher. Electronic reproduction. Amsterdam Elsevier 2017. Available via World Wide Web through ScienceDirect. Nitrogen compounds. Nitric oxide. Electronic books. Doctorovich, Fabio editor. Farmer, Patrick J. editor. Marti, Marcelo A. editor. Electronic Resource https://www.sciencedirect.com/book/9780128009345/the-chemistry-and-biology-of-nitroxyl-hno#book-info Available for University of the Philippines System via ScienceDirect. Click here to access https://www-sciencedirect-com.ezproxy.engglib.upd.edu.ph/book/9780128009345/the-chemistry-and-biology-of-nitroxyl-hno#book-info Also available remotely for University of the Philippines System via ScienceDirect. Click here to access thru EZproxy FO UPD DENG-II QD 181 N1 C44 2017EB Electronic Resource