00000cam a22000004i 4500 UP-99796217613117755 Buklod 20191004120104.0 m |o d | ta 191004s2014 xx d r |||| u| 9781118304730 (cloth : volume 1) (iLib)UPD-00414265550 DLC DSTC rda eng DMLUC R 853 C55 M47 2013 Methods and applications of statistics in clinical trials edited by N. Balakrishnan, McMaster University, Department of Mathematics and Statstics, Hamilton, Ontario, Canada. Hoboken, New Jersey John Wiley & Sons Inc. 2014. 2 volumes illustrations 26 cm text rdacontent unmediated rdamedia volume rdacarrier Wiley series in methods and applications of statistics. Includes bibliographical references and index. Volume 1. Concepts, principles, trials, and design -- volume 2. Planning, analysis, and inferential methods. This comprehensive book features both new and established material on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. It discusses the various kinds of trials that can be found in today's clinical setting including open-labeled trials, multicentered trials, and superiority trials. It also explores such ongoing, cutting-edge trials as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS. Clinical trials Statistical methods. Clinical Trials as Topic. Statistics as Topic. Balakrishnan, N. 1956- editor. FO UPD DSTC R 853 C55 2013 UPD DSTC R 853 C55 M47 2013 Book