Coarse-grained modeling of protein folding through simulated annealing of simplified protein backbones

We have developed Tiklop, a platform to model protein folding at low-resolution. Tiklop is a simulated annealing implementation on a simplified protein backbone representation, which samples possible conformations through constrained pivoting through five ϕ-ψ value pairs, and checks solution fitness...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Manalastas, Karen Katrina G. (VerfasserIn)
Weitere Verfasser: Bongolan, Vena Pearl A. (adviser.)
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: Quezon City College of Engineering, University of the Philippines Diliman 2015.
Schlagworte: