00000cmm a22000004i 4500 UP-99796217611236114 Buklod 20140502082318.0 m go j cr |n |||auu|a 130815s2011 xx u | eng d 9783642129452(e-Book) 3642129455(e-Book) (iLib)UPD-00215705316 DLC DML eng DMLUC SF757.8 S63 2011eb Small animal imaging [electronic resource] basics and practical guide Fabian Kiessling, Bernd J. Pichler (Editors) ; Peter Hauff (co-editor). Berlin Heidelberg Springer c2011. 1 online resource (xvii, 597 p.) ill. (some col.) Noninvasive imaging for supporting basic research -- Noninvasive imaging in the pharmaceutical industry -- How to set up a small animal imaging unit -- Noninvasive small rodent imaging: significance for the 3R principles -- Institutional preconditions for small animal imaging -- Statistical considerations for animal imaging studies -- Animal anesthesia and monitoring -- Drug administration -- How to choose the right imaging modality -- X-ray and X-ray-CT -- CT contrast agents -- Small animal magnetic resonance imaging: basic principles, instrumentation and practical issue -- MR contrast agents -- MR spectroscopy -- Ultrasound -- Ultrasound contrast agents -- PET and SPECT. Radiotracer I: standard tracer -- Radiotracer II: peptide-based radiopharmaceuticals -- Optical imaging -- Optical probes -- Multi-modal imaging and image fusion -- Ex vivo and in vitro cross calibration methods -- In vitro methods for in vivo quantitation of PET and SPECT imaging probes: autoradiography and gamma counting -- Qualitative and quantitative data analysis -- Guidelines for nuclear image analysis -- Kinetic modeling -- Data documentation systems -- Imaging in developmental biology -- Imaging in gynecology research -- Imaging in cardiovascular research -- Imaging in neurology research I: neurooncology -- Imaging in neurology research II: PET imaging in CNS disorders -- Imaging in neurology research III: focus on neurotransmitter imaging -- Imaging in oncology research -- Imaging in immunology research. IP-based subscription, access limited to within on campus computer network. Access via Electronic resources of the UPD University Library Website. Small animal imaging has been recognized as an important tool in preclinical research. Nevertheless, the results of non-invasive imaging are often disappointing owing to choice of a suboptimal imaging modality and/or shortcomings in study design, experimental setup, and data evaluation. This textbook is a practical guide to the use of non-invasive imaging in preclinical research. Each of the available imaging modalities is discussed in detail, with the assistance of numerous informative illustrations. In addition, many useful hints are provided on the installation of a small animal unit, study. Electronic reproduction. New York SpringerLink 2011. Available via World Wide Web through Springerlink. Veterinary diagnostic imaging. Imaging systems in biology. Magnetic resonance imaging. Veterinary radiography. Electronic books. Kiessling, Fabian. Pichler, Bernd J. Hauff, Peter. SpringerLink (Online service). Available for University of the Philippine Diliman via Springerlink. Click here to access http://link.springer.com/book/10.1007/978-3-642-12945-2 FO Monograph UPD DMLR Electronic Resource