00000cmm a22000004i 4500 UP-99796217611235880 Buklod 20140430084410.0 m go j cr |n |||auu|a 101228s2011 xxu u | eng d 9781441973580(e-Book) 1441973583(e-Book) (iLib)UPD-00215705052 DLC DML eng DMLUC RC271C5 P75 2011eb Principles of anticancer drug development [electronic resource] Manuel Hidalgo ... [et al.], editors. New York Springer c2011. 1 online resource (xvii, 673 p.) ill. Basic biostatistics for the clinical trialist / Elizabeth G. Hill and Elizabeth Garrett-Mayer -- Fundamental concepts in clinical pharmacology / Daniel L. Gustafson and Erica L. Bradshaw-Pierce -- Bioanalycial methods in clinical drug development / Walter J. Loos, Peter de Bruijn and Alex Sparreboom -- Preclinical models for anticancer drug development / Edward A. Sausville -- Phase I clinical trials with anticancer agents / Stephen Leong ... [et al.] -- Phase II trials with anticancer agents / Hui K. Gan, J. Jack Lee and Lillian L. Siu -- Phase III clinical trials with anticancer agents / Wendy R. Parulekar and Daniel J. Sargent -- Pharmacokinetic studies in early anticancer drug development / Alex Sparreboom and Sharyn D. Baker -- Pharmacodynamic studies in early phase drug development / D. Ross Camidge, Robert C. Doebele and Antonio Jimeno -- Prediction of antitumor response / Fred R. Hirsch and Yu Shyr -- Imaging studies in anticancer drug development / David A. Mankoff -- Role of the U.S. Food and drug administration in cancer drug development / Ann T. Farrell, Ramzi N. Dagher and Richard Pazdur -- Early clinical trials with cytotoxic agents / M.J.A. de Jonge and Jaap Verweij -- Challenges and successes in developing effective anti-angiogenic agents / Laura Q.M. Chow and S. Gail Eckhardt -- Targeted therapeutics in cancer treatment / Colin D. Weekes and Manuel Hidalgo -- Cancer chemoprevention / Christopher H. Lieu, William N. William Jr. and Scott Lippman -- Combined modality therapy in cancer management / David Raben and Kyle Rusthoven -- Cancer vaccines / Daniel Laheru -- Optimising the development of antibodies as treatment for cancer / Craig P. Carden, Hendrik-Tobias Arkenau and Johann S. de Bono -- Oligonucleotide therapeutics / Cy A. Stein, Britta Hoehn and John Rossi -- Anticancer drug development in pediatric patients / Lia Gore and Margaret Macy -- Clinical trials in special populations / S. Percy Ivy ... [et al.] -- NCI-sponsored clinical trials / Andriana Papaconstantinou and Janet E. Dancey. This is a practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs. Electronic reproduction. New York SpringerLink 2011. Available via World Wide Web through Springerlink. Antineoplastic agents Development. Cancer Treatment. Clinical Trials as Topic. Antineoplastic Agents pharmacokinetics. Neoplasms drug therapy. Cancer Vaccines therapeutic use. Hidalgo, Manuel. Garrett-Mayer, Elizabeth. SpringerLink (Online service). Available for University of the Philippine Diliman via Springerlink. Click here to access http://link.springer.com/book/10.1007/978-1-4419-7358-0 FO UPD DMLR Electronic Resource