00000cmm a22000004a 4500 UP-99796217611211804 Buklod 20140423083645.0 m go j cr cn |||aaaaa 101211s2011 xx u | eng d 9784431538806(eBook) (iLib)UPD-00214607916 DLC DML eng DMLUC QP33.6M36 N65 2011eb Nomura, Taishin. editor. Harnessing Biological Complexity [electronic resource] An Introduction to Computational Physiology Taishin Nomura, Yoshiyuki Asai, editors. Tokyo Springer Japan Imprint: Springer 2011. 1 online resource (vii, 222 p.) Introduction -- II. Modeling Cellular Dynamics -- III. Dynamics of Cellular Networks -- IV. Application of ISIDE to Create Models -- V. Key Consepts of insilicoML. IP-based subscription, access limited to within on campus computer network. Access via Electronic resources of the UPD University Library Website. The challenge for the biosciences in the twenty-first century is to integrate genome sequencing information into a better understanding of biology, physiology, and human pathology. Such attempts at integration are moving the world toward a new generation of bioscience and bioengineering, where biological, physiological, and pathological information from humans and other living animals can be quantitatively described in silico across multiple scales of time and size and through diverse hierarchies of organization ? from molecules to cells and organs, to individuals. To "harness" such complexity, international communities of integrative bioscientists and bioengineers aim to establish frameworks and information infrastructures for describing biological structures and physiological functions on multiple scales of time and space. This textbook includes a public platform to describe physiological functions using mathematical equations and guides the reader to perform mathematical modeling and computer simulations, to combine existing models as well as to create new models. Accessible to biologists, physiologists, and students of the sciences, with illustrative details provided when necessary, this book seeks to achieve a systematic way of harnessing biological complexity. Sharing the databases among communities worldwide will help to find comprehensive answers to all the important questions. Electronic reproduction. New York SpringerLink 2011. Available via World Wide Web through Springerlink. Physiology--Mathematical models. Biological systems Mathematical models. Computational Biology methods. Models, Biological. Electronic books. Asai, Yoshiyuki. editor. Springer eBooks. Printed edition 9783642244247. Available for University of the Philippine Diliman via Springerlink. Click here to access http://link.springer.com/book/10.1007/978-4-431-53880-6 FO Monograph UPD DMLR Electronic Resource