00000cam a22000007a 4500 UP-99796217611057933 Buklod 20140115143139.0 a r |||| u| ta 110826s2012 nyua rb |001 0|eng d 9781617793639 (iLib)UPD-00210204641 DSCI eng QP 551 C516 2012 v.803 Chemical proteomics methods and protocols edited by Gerard Drews and Marcus Bantscheff. New York Humana Press c2012. xi, 313 p. ill. 27 cm. Methods in Molecular Biology 803 Springer protocols Includes bibliographical references and index. Mass spectrometry-based chemoproteomic approaches / Marcus Bantscheff -- Chemical proteomics in drug discovery / Gerard Drewes -- Compound immobilization and drug-affinity chromatography / Uwe Rix, Manuela Gridling, and Giulio Superti-Furga -- Affinity-based chemoproteomics with small molecule-peptide conjugates / Chaitanya Saxena -- A chemical proteomic probe for detecting dehydrogenases : catechol rhodanine / Xia Ge and Daniel S. Sem -- Probing proteomes with benzophenone photoprobes / Akira Kawamura and Doina M. Mihai -- Biotinylated probes for the analysis of protein modification by electrophiles / Simona G. Codreanu ... [et al.] -- Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding proteins by capture compound mass spectrometry / Thomas Lenz ... [et al.] -- Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC / Shao-En Ong ... [et al.] -- Determination of kinase inhibitor potencies in cell extracts by competition binding assays and isobaric mass tags / Carsten Hopf ... [et al.] -- Affinity-based profiling of dehydrogenase subproteomes / Xia Ge and DAniel S. Sem -- Probing the specificity of protein-protein interactions by quantitative chemical proteomics / Duangnapa Kovanich ... [et al.] -- Fluorescence-based proteasome activity profiling / Annamieke de Jong ... [et al.] -- Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions / Mathias Q. M?uller and Andrea Sinz -- Monitoring ligand modulation of protein-protein interactions by chemical cross-linking and high-mass MALDI mass spectrometry / Natalia Gasilova and Alexis Nazabal -- Time-controlled transcardiac perfusion crosslinking for in vivo interactome studies / Amy Hye Won Jeon and Gerold Schmitt-Ulms -- Ligand discovery using small-molecule microarrays / Dominick E. Casalena, Dina Wassaf, and Angela N. Koehler -- Working with small molecules : preparing and storing stock solutions and determination of kinetic solubility / Andrea Wolf, Satoko Shimamura, and Friedrich B.M. Reinhard -- A database for chemical proteomics : ChEBI / Paula de Matos ... [et al.] -- Working with small molecules : rules-of-thumb of drug likeness / Ming-Qiang Zhang. Proteomics Laboratory manuals. Biochemistry Laboratory manuals. Proteomics methods Laboratory Manuals. Chemistry Techniques, Analytical methods Laboratory Manuals. Biochemistry methods Laboratory Manuals. Drewes, Gerard. Bantscheff, Marcus. Methods in molecular biology (Clifton, N.J.) v. 803. Springer protocols. FO UPD DSCI QP 551 C516 2012 v.803 Book