PET-CT image registration in the chest using free-form deformations.

We have implemented and validated an algorithm for three-dimensional positron emission tomography transmission-to-computed tomography registration in the chest, using mutual information as a similarity criterion. Inherent differences in the two imaging protocols produce significant nonrigid motion b...

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Bibliographic Details
Published in:	IEEE Transactions on medical imaging 22, 1 (2003).
Main Author:	Mattes, D.
Format:	Article
Language:	English
Subjects:	100 min. PET-CT image registration. Parzen histogram estimates. Acquisitions. Algorithm. Average computation time. Chest. Closed-form expressions. Criterion. Expert observers. Free-form deformations. Gradient. Hierarchical multiresolution framework. Imaging protocols. Limited-memory quasi-Newton optimization algorithm. Localized cubic B-splines. Moderate-performance workstation. Mutual information. Nonrigid motion. Regular grid. Rigid body deformation. Routine lung cancer staging. Similarity criterion. Specific anatomic locations. Spline-based continuous representation. Split window validation technique. Three-dimensional positron emission tomography transmission-to-computed tomography registration. Validation study. Visually reported errors.