Automated DNA fragments recognition and sizing through AFM image processing.

Automated DNA fragments recognition and sizing through AFM image processing.

This paper presents an automated algorithm to determine DNA fragment size from atomic force microscope images and to extract the molecular profiles. The sizing of DNA fragments is a widely used procedure for investigating the physical properties of individual or protein-bound DNA molecules. Several...

全面介紹

書目詳細資料
發表在:IEEE Transactions on information technology in biomedicine 9, 4 (2005).
主要作者: Ficarra, E.
格式: Article
語言:English
主題:
AFM image processing.
DNA fragment size.
DNA secondary structure transition.
Atomic force microscope images.
Automated DNA fragments recognition.
Automated algorithm.
Background noise.
Computer-generated images.
Image pixel size.
Length estimation.
Manual DNA sizing.
Molecular profile.
Molecular profile extraction.
Physical properties.
Processing time.
Protein-bound DNA molecule.
Root mean square error.
Semiautomated DNA sizing.
Structural analysis.