Cardiac cell networks on elastic microgrooved scaffolds.

We sought to construct a model-engineered cardiac construct having anisotropic properties and consisting of inter-connected cardiac cells with syncytial tissuelike behavior. We report basic structural, electrophysiological and mechanical characterization of multicellular tissuelike engineered constr...

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Bibliographic Details
Published in:	IEEE Engineering in medicine and biology magazine 22, 5 (2003).
Main Author:	Bien, H.
Format:	Article
Language:	English
Subjects:	3-D surface microtopography. Anisotropic properties. Cardiac cell networks. Cardiomyocytes. Elastic microgrooved scaffolds. Electrophysiological characterization. Immunocytochemistry. Interconnected cardiac cells. Master template. Mechanical characterization. Model-engineered cardiac. Multicellular tissuelike engineered constructs. Spatial optical fluorescence. Structural characterization. Syncytial tissuelike behavior.