Effect of solvent on Gd (DOTA)- complex formation a preliminary investigation [Research note]

Effect of solvent on Gd (DOTA)- complex formation a preliminary investigation [Research note]

The thermodynamic stability and kinetic inertness of gadolinium-based MRI contrast agents remains an important research topic in the field of radiological contrast agent development. In this study, the kinetics and thermodynamics of Gd3+-complex formation with the macrocyclic ligand DOTA (i.e., 1,4,...

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Hlavní autoři: Pineda, Ernest Guiller S. (Autor), Villaraza, Aaron Joseph L. (Autor)
Médium: Analytics
Jazyk:English
Vydáno: 2019.
Témata:
Chemistry.
Binding kinetics.
Calorimetry.
Gadolinium-based mri contrast agents.
Isothermal titration ligand exchange reaction.
Solvent effects.
Thermodynamics.
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