In silico studies on N- (Pyridin-2-yl) Thiobenzamides as NNRTIs against wild and mutant HIV-1 strains

In silico studies on N- (Pyridin-2-yl) Thiobenzamides as NNRTIs against wild and mutant HIV-1 strains

In the present study, keeping the Lipinskiâ??s Rule of Five in focus, a series of new 4-(4-benzenesulfonylamino)-N-(5-substituted-pyridin-2-yl)-thiobenzamides bearing different substituents at the C-4 position of benzenesulfonylamino ring have been designed as NNRTIs of wild-type (WT) and mutant HIV...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Singh, Anuradha (Egilea), Singh, Vishal Kumar (Egilea), Verma,Rajesh (Egilea), Singh, Ramendra K. (Egilea)
Formatua: Analytics
Hizkuntza:English
Argitaratua: 2018.
Gaiak:
Chemistry.
Lipinski?s rule of five.
Hiv-1 reverse transcription.
Structure-activity relationships (sars).
Sarrera elektronikoa:https://forms.gle/KZjBv7aRtY6jiL5E9