In silico studies on N- (Pyridin-2-yl) Thiobenzamides as NNRTIs against wild and mutant HIV-1 strains

In silico studies on N- (Pyridin-2-yl) Thiobenzamides as NNRTIs against wild and mutant HIV-1 strains

In the present study, keeping the Lipinskiâ??s Rule of Five in focus, a series of new 4-(4-benzenesulfonylamino)-N-(5-substituted-pyridin-2-yl)-thiobenzamides bearing different substituents at the C-4 position of benzenesulfonylamino ring have been designed as NNRTIs of wild-type (WT) and mutant HIV...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Singh, Anuradha (Συγγραφέας), Singh, Vishal Kumar (Συγγραφέας), Verma,Rajesh (Συγγραφέας), Singh, Ramendra K. (Συγγραφέας)
Μορφή: Analytics
Γλώσσα:English
Έκδοση: 2018.
Θέματα:
Chemistry.
Lipinski?s rule of five.
Hiv-1 reverse transcription.
Structure-activity relationships (sars).
Διαθέσιμο Online:https://forms.gle/KZjBv7aRtY6jiL5E9