00000caa a22000003i 4500 UP-1685594773862388185 Buklod 20210304143129.0 m | | ta 210304s1986 xx r |||| u|eng d (iLib)UPBAG-00039402972 STII-DOST BAG rda eng ARTICLE-2427 Herrera, C.L. author. Preliminary studies on the antifertility activity of Averrhoa bilimbi L. by C. L. Herrera, P. M. Cuasay, E. V. Ramos, Chavez, E. P., L. A. Dayap and B. C. Rabang. 1986. pages 307-316 26 cm text rdacontent unmediated rdamedia volume rdacarrier Includes bibliographical references (page 311) and index. This paper involves preliminary studies to verify the previously reported antifertility activity in sows by "kamias" (Averrhoa bilimbi L.) fruit using a modified Female Mouse Fertility Screening Method. Enovid (norethynodrel-mestranol), a commercial drug was used as a positive control while the solvent used to dissolve the test drug was used as negative control. The juice obtained from 5 g, 10 g, and 20 g fresh fruit per kg body weight were tested for antifertility activity and the largest dose equivalent to 14.4 mL/kg reduced the fertility rate of mice by 50% compared with the control. The ethanol extract of the dried fruit produced the same effect at a dose of 1 g/kg. Population experiments on the same extract produced the same results. The butanol fraction of the ethanol extract containing the steroidal glycoside and potassium oxalate gave the same effect at 120 mg/kg dose. Pharmacodynamics. Averrhoa bilimbi Antifertility properties. Kamias. Cuasay, P.M. author. Ramos, E.V. author. Chavez, E.P. author. Dayap, L..A. author. Rabang, B.C. author. The Philippine Journal of Science Vol. 115, no.4, October-December 1986. Request full-text access via UPB University Library through https://forms.gle/KZjBv7aRtY6jiL5E9 (viewed 04 March 2021) FI UPBAG UPBAG-MAIN ARTICLE-2427 Analytics