00000cam a22000004a 4500 UP-1685523046126355195 Buklod 20240306180519.0 aa r |||| u| ta 240306s2019 xx d |||| || | 0702072990 (paperback) 9780702072994 (paperback) (iLib)UPMNL-00016765597 MED rda eng QP 514.2 B39 2019 Baynes, John W. author. Medical biochemistry John W. Baynes, Marek H. Dominiczak. Fifth edition. [Edinburgh] Elsevier 2019. xxvi, 682 pages illustrations 28 cm. text txt rdacontent. unmediated rdamedia. volume nc rdacarrier. Includes bibliographical references and index. I: Introduction -- Introduction / John W. Baynes, Marek H. Dominiczak -- II: Molecules and cells -- Amino acids and proteins -- Carbohydrates and lipids -- Membranes and transport -- III: Metabolism -- Hemoglobin and oxygen transport -- Catalytic proteins-enzymes -- Vitamins and minerals -- Bioenergetics and oxidative metabolism -- Anaerobic metabolism of glucose carbohydrates in the red blood cell -- The tricarboxylic acid cycle -- Oxidative metabolism of lipids in liver and muscle -- Biosynthesis and storage of carbohydrates in liver and muscle -- Biosynthesis and storage of fatty acids -- Biosynthesis of cholesterol and steroids -- Biosynthesis and degradation of amino acids -- Biosynthesis and degradation of nucleotides -- Complex carbohydrates: glycoproteins -- Complex lipids -- The extracellular matrix -- IV: Molecular basis of inheritance -- Deoxyribonucleic acid -- Ribonucleic acid -- Protein synthesis and turnover -- Regulation of gene expression: basic mechanisms -- Genomics, proteomics and metabolomics -- V: Signalling and growth -- Membrane receptors and signal transduction -- Neurotransmitters -- Biochemical endocrinology -- Cellular homeostasis: cell growth and cancer -- Aging -- VI: Fuels nutrients and minerals -- Digestion and absorption of nutrients: the gastrointestinal tract -- Glucose homeostasis and fuel metabolism: diabetes mellitus -- Nutrients and diets -- Lipoprotein metabolism and atherogenesis -- VII: Specialized tissues and their function -- The role of liver in metabolism -- Water and electrolytes homeostasis -- Lung and the regulation of hydrogen ion concentration (Acid-base balance) -- Muscle: energy metabolism and contraction exercise -- Bone metabolism and calcium homeostasis -- Neurochemistry -- VIII: Blood and Immunity. Clinical biochemistry -- Blood and plasma proteins -- Haemostasis and thrombosis -- Oxidative stress and inflammation -- The immune response: innate and adaptive immunity -- Appendix 1: Selected clinical laboratory reference ranges -- Appendix 2: Case stud. "Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues-including diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease-and addresses the role of nutrition and exercise in medicine." [back cover]. Biochemistry. Clinical biochemistry. Biochemical Phenomena. Biochemistry methods. Dominiczak, Marek H. author. FO UPMNL MED QP 514.2 B39 2019 Book