00000ctm a22000003a 4500 UP-1685523046126318424 Buklod 20170814153733.0 m |o d | ta 170814s2017 xx d r |||| u| (iLib)UPMNL-00015498141 UPM PHARM rda eng LG 993.5 2017 P5 M35 Malate, Jameca Mae M. author. Drug utilization review of antipsychotic agents for inpatient treatment of schizophrenia in a tertiary government hospital Jameca Mae M. Malate, Maria Rosewynn Anne R. Salvan, Mara Angeli V. Sarabillo ; adviser, Edwin C. Ruamero. ​​​​​​​​​​Manila: Department of Pharmacy, College of Pharmacy, University of the Philippines Manila 2017. ​​ viii, 66 leaves 28 cm. ​​​​text rdacontent unmediated rdamedia volume rdacarrier Available to the general public. ​​​​​​Thesis (Bachelor of Science in Pharmacy)--University of the Philippines Manila, June 2017. Among the most common mental illnesses afflicting Filipinos, schizophrenia is the leading condition for which patients seek consultation and treatment. Medications typically used for this condition are antipsychotics, which are associated with multiple adverse effects, interactions and contraindications that complicate treatment. The objective of this study was to evaluate the drug utilization of antipsychotic drugs for the treatment of schizophrenia among inpatients in a tertiary government hospital, in terms of demographics, drug therapy problems, and compliance with the local treatment guidelines released by the National Center for Mental Health (2011). For this purpose, review of patient medical charts was done to gather the data necessary to accomplish the set objectives. Descriptive statistics were used to analyze the data. The results showed that most of the patients who were given antipsychotics for treatment of schizophrenia were in the 25 to 31-year- old age group (27.5%) and are male (56.9%). Other mental health problems such as major depressive disorder and bipolar disorder are the most common comorbidities among patients (8.26%). Risperidone, Olanzapine and Haloperidol are among the top prescribed antipsychotic agents among in- patients diagnosed with schizophrenia. Drug-drug interactions are the most common drug therapy problems among the cases (75.2%). Only 58.7% of the cases complied with the set standard treatment guidelines, with prescribing of the incorrect dosage (83.8%) and therapeutic duplication (16.2%) as the reasons for non-compliance. Most of the cases exhibited moderate to high appropriateness of antipsychotic utilization in the ward using the Medication Appropriateness Index as adapted from that devised by Samsa, et al. (1994). Drug utilization. Schizophrenia. Antipsychotic drugs. Salvan, Maria Rosewynn Anne R. author. Sarabillo, Mara Angeli V.,​​ author. Ruamero, Edwin C. thesis adviser. FI UP UPMNL PHARM LG 993.5 2017 P5 M35 Thesis