00000ctm a22000003a 4500 UP-1685523046126318069 Buklod 20170331163813.0 m |o d | ta 170331s xx d r |||| u| (iLib)UPMNL-00015383018 UPM-PHARM eng LG993.5 2014 P5 C6 Concepcion, Roseval Evaluation of Arenga saccharifera Labill (Fam. Arecaceae) seed gum as tablet binder Concepcion, Roseval; Gomez, Clinton B.;Urias, Justine C. 63 leaves Undergraduate Theses(BS in Pharmacy)--University of the Philippines Manila, 2016. New sources of natural polymers may provide pharmaceutical excipients that posses economy of preparation, ready availability, non-toxicity, biodegradability, and eco-friendly processing. Mature nuts of Arenga saccharifera Labill (Fam arecaceae), (syn. Arenga pinnata Wurmb Merr.) locally known as 'kaong? (sugar palm), have been found to contain gum that may be used as tablet binders. The gum from the endosperm was extracted, characterized, and formulated to plain uncoated Paracetamol tablets to compare its binding property to that of Acacia gum and polyvinylpyrrolidone (PVP). In-process Quality Control tests of the granules revealed excellent flow properties for A. saccharifera gum. Furthermore, greater amount of good granules were obtained from the A. saccharifera gum, compared to the other binders. The result of the dissolution test showed tablets prepared using 5% A. saccharifera gum had a better release of the drug compared to the tablets prepared using 5% acacia while tablets produced using 5% PVP failed the test. In conclusion, the gum extracted from A. saccharifera nuts has satisfactory binding properties and can be used in tablet formulations. Gomez, Clinton B. Urias, Justine C. Fi UPMNL PHARM LG993.5 2014 P5 C6 Thesis