00000cam a22000004a 4500 UP-1685523046126222250 Buklod 20111109165836.0 m |o d | ta 111109s2011 xx d r |||| u| 9780470684467 (iLib)UPMNL-00012156723 Ph-8468 Forefront Php5117.00 UPM PHARM eng RM 301.5 C863 2011 Curry, Stephen H. Drug disposition and pharmacokinetics from principles to applications Stephen H. Curry, Robin Whelpton. Chichester, West Sussex Wiley-Blackwell c2011. xix, 365 p. ill. 26 cm. text rdacontent unmediated rdamedia volume rdacarrier Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology. Pharmacokinetics. Biopharmaceutics. Drugs Metabolism. Pharmacokinetics. Biopharmaceutics. Pharmaceutical Preparations metabolism. Whelpton, Robin. FO UPMNL PHARM RM 301.5 C863 2011 Book