Use of PCR in the amplification of the rpoB gene of some Philippine mycobacterium tuberculosis isolates and SSCP analysis of rimfampicin resistance
Mycobacterial rpoB gene is the structural gene that codes for the synthesis of bacterial RNA polymerase. Presence of mutations in the rpoB gene of Mycobacterium tuberculosis alters the sequence of amino acids in bacterial RNA polymerase essential for rifampicin binding. Such mechanism allows for...
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| Format: | Thesis |
| Language: | English |
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