00000ctm a22000007a 4500 UP-1685523046125413732 Buklod 20230503092606.0 m |o d | ta 071031s xx d r |||| u| (iLib)UPMNL-00000055080 ​​​​UPM PHARM eng LG 995 1970 P41 T54 Tiemsakul, Thanomsri 1941- The alkaloids of the leaves of Alstonia macrophylla Wall. (Fam. Apocynaceae) Thanomsri Tiemsakul. 75 leaves Available to the general public. Thesis (Master of Science in Pharmaceutical Chemistry)--University of the Philippines, 1970. The ethereal extract of the leaves of Alstonia macrophylla Wall. (Fam. Apocynaceae) showed by thin layer chromatography the presence of five tertiary alkaloids and the absence of quaternary alkaloids. Of the alkaloids present, alkaloid x was isolated as white needle-like crystals, m.p. 210-212(degrees C) (dec.). Due to a very small yield of the isolated alkaloid (0.0005%), physicochemical methods were used in elucidating the possible structure. It did not correspond to any of the alkaloids previously isolated from Alstonia macrophylla Wall. It was found to be an indoline base with an ajamaline-sarpagine nucleus and containing one hydroxyl and one carbomethoxyl group. The molecular formula was established by mass spectrometry to be C21H24N2 03. Alkaloids. Alstonia macrophylla wall. FI UP UPMNL PHARM LG 995 1970 P41 T54 Thesis