00000cab a22000004cb4500 IPP-00000189341 IPP 20200702040650.0 200702s2014 xx d | ||r |||||eng|| eng Torres, Charmaine G. Bio-assay- guided fractionation and chromatographic profiling of the hexane extract from the leaves of "tanga-tanga", Prunus Grisea. 2014 illustrations Prunus Grisea, locally known as "tanga-tanga", belongs to the Rosacae family and Genus Prunus. This study is focused on the bioassay-guided partial isolation of the bioactive fractions from the hexane extract of the air-dried leaves of Prunus grisea, denoted as PGH, employing various chromatographic methods. Gravity column chromatography of PGH afforded the 14 fractions PGH1-PGH14. Fraction PGH13 exhibited the highest bioactivity against the brine shrimp Artemia salina Leach with mortality of 56.67%. Subsequent purification of fraction PGH13 gave the six sub-fractions PGH13.1-PGH13.6 which were subjected to high-performance liquid chromatographic profiling and analysis. These possibly purified sub-fractions were identified and recommended for structure elucidation and further bioactivity tests. Chromatographic analysis High performance liquid chromatography Uy, Mylene M. Asia-Pacific Journal of Science, Mathematics, and Engineering Vol. 2, no. 1 (2014), 17-20 UPD DMLP Article FI