00000cab a22000004cb4500 IPP-00000117121 IPP 20200702040655.0 200702s2012 xx d | ||r |||||eng|| eng Magbitang, Riza A. Cadmium and lead determination by ICPMS method optimization and application in carabao milk samples 2012 illustrations, tables, bibliography A method utilizing inductively coupled plasma mass spectrometry (ICPMS) as the element-selective detector with microwave-assisted nitric acid digestion as the sample pre-treatment technique was developed for the simultaneous determination of cadmium (Cd) and lead (Pb) in milk samples. The estimated detection limits were 0.09µg kg-1 and 0.33µg kg-1 for Cd and Pb, respectively. The method was linear in the concentration range 0.01 to 500µg kg-1with correlation coefficients of 0.999 for both analytes. The method was validated using certified reference material BCR 150 and the determined values for Cd and Pb were 18.24 ± 0.18 µg kg-1 and 807.57 ± 7.07µg kg-1, respectively. Further validation using another certified reference material, NIST 1643e, resulted in determined concentrations of 6.48 ± 0.10 µg L-1 for Cd and 21.96 ± 0.87 µg L-1 for Pb. These determined values agree well with the certified values in the reference materials. The method was applied to processed and raw carabao milk samples collected in Nueva Ecija, Philippines. The Cd levels determined in the samples were in the range 0.11 ± 0.07 to 5.17 ± 0.13 µg kg-1 for the processed milk samples, and 0.11 ± 0.07 to 0.45 ± 0.09 µg kg-1 for the raw milk samples. The concentrations of Pb were in the range 0.49 ± 0.21 to 5.82 ± 0.17 µg kg-1 for the processed milk samples, and 0.72 ± 0.18 to 6.79 ± 0.20 µg kg-1 for the raw milk samples. [ABSTRACT FROM AUTHOR] Inductively coupled plasma mass spectrometry Milk contamination Milk Composition Water buffalo Milk yield Rodriguez, Irene B. Science Diliman Vol. 24, no. 1 (Jan. 2012 - Jun. 2012), 1-11 UPD DMLP Article FI